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[texts]Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. (Volume 20) - Abad, Sebastien
This article is from Molecular Vision, volume 20.AbstractPurpose: Vogt-Koyanagi-Harada (VKH) syndrome is an autoimmune disease characterized by inaugural uveomeningitidis and hearing loss and at late stages a depigmentation in eyes and skin. Melanocytes are the cells common to the four affected tissues, namely eye, brain, inner ear, and skin. Melanocytes are therefore considered as the source of self-antigens...
Downloads: 3
[texts]S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis. (Volume 20) - Abu El-Asrar, Ahmed M.
This article is from Molecular Vision, volume 20.AbstractPurpose: The calcium-binding protein S100A4 is implicated in cancer cell invasion and metastasis, the stimulation of angiogenesis, the progression of fibrosis, and inflammatory disorders. We investigated the expression of S100A4 and correlated it with clinical disease activity as well as with the levels of osteopontin (OPN), soluble syndecan-1, and vascular endothelial growth factor (VEGF) in proliferative diabetic retinopathy (PDR)...
Downloads: 3
[texts]Identification of recurrent and novel mutations in TULP1 in Pakistani families with early-onset retinitis pigmentosa. (Volume 18) - Ajmal, Muhammad
This article is from Molecular Vision, volume 18.AbstractPurpose: To identify the genetic defects underlying retinitis pigmentosa (RP) in Pakistani families. Methods: Genome-wide high-density single-nucleotide-polymorphism microarray analysis was performed using the DNA of nine affected individuals from two large families with multiple consanguineous marriages. Data were analyzed to identify homozygous regions that are shared by affected sibs in each family...
[texts]Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. (Volume 18) - Baas, Dominique C.
This article is from Molecular Vision, volume 18.AbstractPurpose: Age-related macular degeneration (AMD) is a major cause of blindness in older adults and has a genetically complex background. This study examines the potential association between single nucleotide polymorphisms (SNPs) in the glucose transporter 1 (SLC2A1) gene and AMD. SLC2A1 regulates the bioavailability of glucose in the retinal pigment epithelium (RPE), which might influence oxidative stress–mediated AMD pathology...
Downloads: 1
[texts]TECHNICAL BRIEF: Optimized pipeline for isolation of high-quality RNA from corneal cell subpopulations. (Volume 20) - Bath, Chris
This article is from Molecular Vision, volume 20.AbstractPurpose: Attempts to determine the transcriptional profile of discrete subsets of limbal epithelial cells in situ using laser capture microdissection (LCM) face two major challenges. First, the transcriptional profile of cells within a tissue may rapidly change as the tissue is excised and exposed to cold ischemia. Second, there is a risk of degradation of the RNA as the cellular compartment is separated from the remaining tissue...
Downloads: 2
[texts]Ham and Dixie : a just, simple and original discussion of the southern problem - Capponi, Joseph Burritt Sevelli
Electronic reproduction
Keywords: Black race; African Americans
Downloads: 118
[texts]Expression profile of inflammatory cytokines in aqueous from glaucomatous eyes. (Volume 18) - Chua, Jocelyn
This article is from Molecular Vision, volume 18.AbstractPurpose: To determine the proinflammatory cytokine profile of aqueous humor from glaucomatous eyes. Methods: Aqueous humor samples were prospectively collected from 38 eyes (26 primary open angle glaucoma [POAG] and 12 primary angle closure glaucoma [PACG] eyes) of 37 medically treated glaucoma patients and 23 cataract subjects recruited in an institutional setting in this case-controlled study...
Downloads: 1
[texts]The past, present, and future in prose and poetry - Clark, B
Electronic reproduction
Keywords: African Americans
Downloads: 83
[texts]Correspondence and remarks on two occasions in the Senate of Virginia, on the subject of martial law and arrests and confinement of civilians by military orders - Collier, Robert R. (Robert Ruffin), 1805-1870
Crandall, M.L. Confederate imprints
Keywords: Martial law
Downloads: 78
[texts]Three Catholic Afro-American congresses : a short resume of the work that has been done since the Third Plenary Council of Baltimore, letters of the hierarchy, clergy and prominent laymen to the congresses, the sermons of Cardinal Gibbons, Archbishop Elder, Archbishop Ryan and Father Mackey, speeches and portraits of prominent colored Catholics, their friends and institutions, the public addresses of the three most remarkable gatherings of Negroes in America : all nicely bound in cloth - Congress of Colored Catholics of the United States
Proceedings of three congresses: the 1st held Jan. 1-3, 1889 in Washington, D.C., the 2nd held July 8-11, 1890 in Cincinnati, and the 3rd held Jan. 5-7, 1892 in Philadelphia
Keywords: African American Catholics
Downloads: 138
[texts]Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5. (Volume 19) - Cottet, Sandra
This article is from Molecular Vision, volume 19.AbstractPurpose: To analyze in vivo the function of chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C (gene symbol: Cspg5) during retinal degeneration in the Rpe65−/− mouse model of Leber congenital amaurosis. Methods: We resorted to mice with targeted deletions in the Cspg5 and retinal pigment epithelium protein of 65 kDa (Rpe65) genes (Cspg5−/−/Rpe65−/−)...
Downloads: 3
[texts]TMEM126A mutation in a Moroccan family with autosomal recessive optic atrophy. (Volume 18) - Desir, Julie
This article is from Molecular Vision, volume 18.AbstractPurpose: Nonsyndromic autosomal recessive optic atrophy (arOA) is extremely rare and its existence was disputed until a locus, optic atrophy 6 (OPA6), was mapped to 8q. Recently, a second locus, OPA7, was found on 11q in several families from North Africa, with one presumably ancestral mutation of transmembrane protein 126A (TMEM126A). Here we report an independently ascertained large consanguineous family of Moroccan descent with three si...
Downloads: 2
[texts]Oration delivered in Corinthian Hall, Rochester - Douglass, Frederick, 1818-1895
"Published by request."
Keywords: Slavery
Downloads: 72
[texts]South-western Methodism ; a history of the M. E. Church in the South-west, from 1844 to 1864. - Elliott, Charles, 1792-1869
Electronic reproduction
Keywords: Methodist Episcopal Church; Methodist Church
Downloads: 192
[texts]Dedication of the library building, Gammon Theological Seminary, May 26th, 1889, 2:30 p.m., Atlanta, Ga - Gammon Theological Seminary
Cover title
Keywords: Gammon Theological Seminary; Library buildings; Dedication services
Downloads: 49
[texts]Le antichita della citta di Roma : raccolte sotto breuita da diuersi antichi & moderni scrittori - Gamucci, Bernardo
Imprint from colophon
Keywords: Architecture
Downloads: 115
[texts]The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort. (Volume 19) - Garcia-Garcia, Gema
This article is from Molecular Vision, volume 19.AbstractBackground: Usher syndrome type 2 (USH2) is an autosomal recessive disease characterized by moderate to severe hearing loss and retinitis pigmentosa. To date, three disease-causing genes have been identified, USH2A, GPR98, and DFNB31, of which USH2A is clearly the major contributor. The aim of this work was to determine the contribution of GPR98 and DFNB31 genes in a Spanish cohort of USH2A negative patients using exhaustive molecular anal...
Downloads: 1
[texts]Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification. (Volume 18) - Hazra, Sarbani
This article is from Molecular Vision, volume 18.AbstractPurpose: To evaluate the effect of ethylenediaminetetraacetic acid (EDTA) on posterior capsular opacification (PCO) of rabbits and to assess its effect on intraocular tissues. Methods: Modulation of matrix metalloproteinase (MMP) activity in the aqueous following cataract surgery in rabbits and its prevention by different doses of EDTA was determined by zymography...
Downloads: 3
[texts]Quiescent keratocytes fail to repair MMC induced DNA damage leading to the long-term inhibition of myofibroblast differentiation and wound healing. (Volume 18) - Jester, James V.
This article is from Molecular Vision, volume 18.AbstractPurpose: The purpose of this study was to determine the acute and long-term effects of mitomycin C (MMC) on quiescent rabbit corneal keratocytes regarding cell proliferation, myofibroblast differentiation and DNA repair. Methods: Quiescent keratocytes cultured in serum-free media were exposed to various concentrations of MMC and then treated with transforming growth factor-β (TGFβ)...
Downloads: 1
[texts]Structural analysis of the mutant protein D26G of human ?S-crystallin, associated with Coppock cataract. (Volume 19) - Karri, Srinivasu
This article is from Molecular Vision, volume 19.AbstractPurpose: To analyze the protein structural features responsible for the aggregation properties of the mutant protein D26G human γS-crystallin (HGSC) associated with congenital Coppock-type cataract. Methods: cDNAs of wild-type (WT) and D26G mutant HGSC were cloned and expressed in BL21 (DE3) pLysS cells and the proteins isolated and purified...
Downloads: 3
[texts]Decrease in hyperosmotic stress-induced corneal epithelial cell apoptosis by L-carnitine. (Volume 19) - Khandekar, Neeta
This article is from Molecular Vision, volume 19.AbstractPurpose: To characterize the osmoprotective properties of L-carnitine on human corneal epithelial cell volume and apoptosis during hyperosmotic stress. Methods: Human corneal limbal epithelial (HCLE) cells were exposed to culture medium at 300 mOsm (isotonic) or 500 mOsm (hyperosmotic) with or without L-carnitine (10 mM). Induction of apoptosis was detected by quantifying the proteolytic activity of caspase-8, caspase-9, and caspase-3/7 us...
[texts]Mutation analysis of the SLC4A11 gene in Indian families with congenital hereditary endothelial dystrophy 2 and a review of the literature. (Volume 19) - Kodaganur, Srinivas Gopinath
This article is from Molecular Vision, volume 19.AbstractPurpose: Congenital hereditary endothelial dystrophy 2 (CHED2) is an autosomal recessive disorder caused by mutations in the solute carrier family 4, sodium borate transporter, member 11 (SLC4A11) gene. The purpose of this study was to identify the genetic cause of CHED2 in six Indian families and catalog all known mutations in the SLC4A11 gene...
Downloads: 2
[texts]Calcium-independent phospholipase A2, group VIA, is critical for RPE cell survival. (Volume 20) - Kolko, Miriam
This article is from Molecular Vision, volume 20.AbstractPurpose: To investigate the significance of calcium-independent phospholipase A2, group VIA (iPLA2-VIA), in RPE cell survival following responses to sodium iodate (SI) in cell cultures. Methods: The human retinal pigment epithelium (RPE) cell line (ARPE-19) cells and primary mouse-RPE cultures were treated with SI to induce cell death. Cells were transfected with an iPLA2-VIA promoter-luciferase construct to evaluate the regulation of iPLA...
Downloads: 1
[texts]Spatial expression of aquaporin 5 in mammalian cornea and lens, and regulation of Its localization by phosphokinase A. (Volume 18) - Kumari, S. Sindhu
This article is from Molecular Vision, volume 18.AbstractPurpose: Aquaporins (AQPs) play a significant role in the movement of water across the plasma membrane. In the eye, the cornea and lens are avascular with unique microcirculatory mechanisms to meet the metabolic demands. We have previously shown that AQP0 and AQP1 water channels participate in maintaining lens transparency and homeostasis. In the present investigation, we explored the expression and spatial distribution of AQP5 in the corn...
Downloads: 1
[texts]Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1?, tumor necrosis factor-?, and interferon-? (Volume 19) - Kutty, R. Krishnan
This article is from Molecular Vision, volume 19.AbstractPurpose: The inflammatory response of the retinal pigment epithelium (RPE) is implicated in the pathogenesis of age-related macular degeneration. The microRNAs miR-146a and miR-146b-5p can regulate the inflammatory process by attenuating cytokine signaling via the nuclear factor-κB pathway. The aim of the present study is to investigate the expression of miR-146a and miR-146b-5p in human RPE cells and their response to proinflammatory cyt...
Downloads: 1
[texts]Increase in retinal ganglion cells' susceptibility to elevated intraocular pressure and impairment of their endogenous neuroprotective mechanism by age. (Volume 19) - Levkovitch-Verbin, Hani
This article is from Molecular Vision, volume 19.AbstractPurpose: To investigate age-associated changes in retinal ganglion cell (RGC) response to elevated intraocular pressure (IOP), and to explore the mechanism underlying these changes. Specifically, the effect of aging on inhibitor of apoptosis (IAP) gene family expression was investigated in glaucomatous eyes. Methods: IOP was induced unilaterally in 82 Wistar rats using the translimbal photocoagulation laser model...
Downloads: 1
[texts]Ocular fibroblast types differ in their mRNA profiles--implications for fibrosis prevention after aqueous shunt implantation. (Volume 19) - Lobler, Marian
This article is from Molecular Vision, volume 19.AbstractPurpose: For an aqueous shunt draining from the anterior chamber into the choroidal space, fibroblasts from the choroidea and/or the sclera are most likely responsible for a fibrotic response around the outflow region of such a shunt. The prevention of fibrosis should extend the operating life of the shunt. A detailed characterization of fibroblasts derived from choroidea and sclera should provide information about whether a fibrosis react...
Downloads: 1
[texts]Noted Negro women : their triumphs and activities - Majors, Monroe A. (Monroe Alphus), b. 1864
Electronic reproduction
Keywords: African American women; African Americans
Downloads: 359
[texts]Protein changes in the retina following experimental retinal detachment in rabbits. (Volume 17) - Mandal, Nakul
This article is from Molecular Vision, volume 17.AbstractPurpose: Retinal detachment leads to the widespread cellular remodeling of the retina. The purpose of this study was to identify protein changes that accompany these cellular alterations by comparing the proteomic profiles of sham and experimentally detached rabbit retina. Elucidation of the proteins most dramatically affected by retinal detachment would add further understanding to the pathophysiology of this condition, and potentially id...
Downloads: 1
[texts]Slavery in Kentucky, 1792-1865 - McDougle, Ivan E. (Ivan Eugene)
"Reprinted from The Journal of Negro History, Vol. III, No. 3, July, 1918"
Keywords: Slavery
Downloads: 3
[texts]Whole-exome sequencing identifies novel compound heterozygous mutations in USH2A in Spanish patients with autosomal recessive retinitis pigmentosa. (Volume 19) - Mendez-Vidal, Cristina
This article is from Molecular Vision, volume 19.AbstractPurpose: Retinitis pigmentosa (RP) is an inherited retinal dystrophy characterized by extreme genetic and clinical heterogeneity. Thus, the diagnosis is not always easily performed due to phenotypic and genetic overlap. Current clinical practices have focused on the systematic evaluation of a set of known genes for each phenotype, but this approach may fail in patients with inaccurate diagnosis or infrequent genetic cause...
Downloads: 3
[texts]In the Chancery Court of Davidson County, Tenn., rule no. 27177, October term, 1910, state of Tennessee, on the relation of A.W. Wilson and others, composing the College of Bishops, of the Methodist Episcopal Church, South, and others, complainants, against the Board of Trust of Vanderbilt University, and others, defendants : original bill of complainants and answer thereto of defendants - Methodist Episcopal Church, South. College of Bishops, complainant
The online edition of this book in the public domain, i.e., not protected by copyright, has been produced by the Emory University Digital Library Publications Program
Keywords: Methodist Episcopal Church, South; Vanderbilt University; Church and college; Universities and colleges
Downloads: 4
[texts]The Afro-American almanac 1901 - Mexican Mustang Liniment Company
Cover title
Keywords: African Americans; Patent medicines
Downloads: 116
[texts]WDR36 variants in East Indian primary open-angle glaucoma patients. (Volume 17) - Mookherjee, Suddhasil
This article is from Molecular Vision, volume 17.AbstractPurpose: Glaucoma is a heterogeneous group of optic neuropathies with a complex genetic basis. To date, only the following four genes have been identified: viz. myocilin (MYOC), optineurin (OPTN), WD repeat domain 36 (WDR36), and neurotrophin 4 (NTF4). However, there are conflicting reports regarding the involvement of WDR36 in the pathogenesis of primary open-angle glaucoma (POAG)...
Downloads: 5
[texts]A short history of Independent Methodism : a souvenir of the hundredth annual meeting of the Independent Methodist Churches, 1905 - Mounfield, Arthur
The General Committee of the Independent Methodist Churches "decided upon the issue of the present volume and entrusted its preparation to George Hunter, James Vickers, and Arthur Mounfield
Keywords: Independent Methodist Churches (England); Methodist Church
Downloads: 186
[texts]Adnotationes et meditationes in Euangelia quae in sacrosancto Missae sacrificio toto anno leguntur : cum eorundem Euangeliorum concordantia - Nadal, Gerónimo, 1507-1580
Engraved t.p
Keywords: Jesus Christ; Bible; Bible
Downloads: 56
[texts]Effects of topically applied tocotrienol on cataractogenesis and lens redox status in galactosemic rats. (Volume 20) - Nasir, Nurul Alimah Abdul
This article is from Molecular Vision, volume 20.AbstractPurpose: Oxidative and nitrosative stress underlies cataractogenesis, and therefore, various antioxidants have been investigated for anticataract properties. Several vitamin E analogs have also been studied for anticataract effects due to their antioxidant properties; however, the anticataract properties of tocotrienols have not been investigated...
Downloads: 2
[texts]A novel MERTK deletion is a common founder mutation in the Faroe Islands and is responsible for a high proportion of retinitis pigmentosa cases. (Volume 17) - Ostergaard, Elsebet
This article is from Molecular Vision, volume 17.AbstractPurpose: The aim of the study was to elucidate the genetic background of retinitis pigmentosa (RP) in a Faroe Islands population, a genetic isolate in the North Atlantic Ocean. Methods: Blood samples were collected from subjects diagnosed with RP and their families. DNA from affected individuals underwent single nucleotide polymorphism microarray analysis and homozygosity mapping followed by sequence analysis of candidate genes...
Downloads: 4
[texts]Retinal nerve fiber hypertrophy in ataxia of Charlevoix-Saguenay patients. (Volume 17) - Pablo, Luis E
This article is from Molecular Vision, volume 17.AbstractPurpose: To present full ophthalmologic examination and retinal nerve fiber layer (RNFL) photographs of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) patients showing significant increases in RNFL thickness compared to healthy subjects, but without myelinated retinal fibers. Methods: The study design was observational case series...
Downloads: 8
[texts]Common TGFβ2, BMP4, and FOXC1 variants are not associated with primary open-angle glaucoma. (Volume 18) - Park, Soo
This article is from Molecular Vision, volume 18.AbstractPurpose: Primary open-angle glaucoma (POAG) is a common but complex disease with a strong genetic component. Notably, few genes have been robustly associated with POAG. An obvious group of genes to test as susceptibility factors for POAG are the developmental genes forkhead box C1 (FOXC1), transforming growth factor-beta 2 (TGFβ2), and bone morphogenic protein 4 (BMP4)...
Downloads: 1
[texts]Clinical evaluation of two consanguineous families with homozygous mutations in BEST1. (Volume 17) - Pineiro-Gallego, Teresa
This article is from Molecular Vision, volume 17.AbstractPurpose: To describe the clinical and genetic findings in two consanguineous families with Best vitelliform macular dystrophy (BVMD) and homozygous mutations in the bestrophin-1 (BEST1) gene. Methods: Ophthalmologic examination was performed in eight members of two families originating from Spain and Denmark. Mutation screening was performed using the Vitelliform Macular Dystrophy mutation array from Asper Biotech, and by the directed geno...
Downloads: 1
[texts]Autobiography of a thief and Jack of all trades, a matter-of-fact romance - Reade, Charles, 1814-1884
Bound in illustrated paper-covered boards
Downloads: 7
[texts]A family with Wagner syndrome with uveitis and a new versican mutation. (Volume 19) - Rothschild, Pierre-Raphael
This article is from Molecular Vision, volume 19.AbstractPurpose: To report the clinical and molecular findings of a kindred with Wagner syndrome (WS) revealed by intraocular inflammatory features. Methods: Eight available family members underwent complete ophthalmologic examination, including laser flare cell meter measurements. Collagen, type II, alpha 1, versican (VCAN), frizzled family receptor 4, low density lipoprotein receptor-related protein 5, tetraspanin 12, and Norrie disease (pseudog...
Downloads: 3
[texts]Differential expression of the Slc4 bicarbonate transporter family in murine corneal endothelium and cell culture. (Volume 19) - Shei, William
This article is from Molecular Vision, volume 19.AbstractPurpose: To characterize the relative expression levels of all the solute carrier 4 (Slc4) transporter family members (Slc4a1–Slc4a11) in murine corneal endothelium using real-time quantitative (qPCR), to identify further important members besides Slc4a11 and Slc4a4, and to explore how close to the baseline levels the gene expressions remain after cells have been subjected to expansion and culture...
Downloads: 1
[texts]Nectin-1-specific entry of herpes simplex virus 1 is sufficient for infection of the cornea and viral spread to the trigeminal ganglia. (Volume 18) - Shukla, Navika D.
This article is from Molecular Vision, volume 18.AbstractPurpose: Primary and recurrent infections of the cornea by herpes simplex virus 1 (HSV-1) are important causes of eye disease. Three unrelated classes of glycoprotein D receptors for HSV-1 entry into cells have been identified. This study was undertaken to uncover the relative significance of nectin-1 as an entry receptor in corneal infection and HSV-1 spread to the trigeminal ganglia (TG), a site important for HSV-1 latency and recurrent ...
Downloads: 2
[texts]Novel compound heterozygous NMNAT1 variants associated with Leber congenital amaurosis. (Volume 20) - Siemiatkowska, Anna M.
This article is from Molecular Vision, volume 20.AbstractPurpose: The gene encoding nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) was recently found to be mutated in a subset of patients with Leber congenital amaurosis (LCA) with macular atrophy. The aim of this study was to determine the occurrence and frequency of NMNAT1 mutations and associated phenotypes in different types of inherited retinal dystrophies...
Downloads: 2
[texts]The adventures of Mr. Ledbury and his friend Jack Johnson - Smith, Albert, 1816-1860
Bound in illustrated paper-covered boards
Downloads: 447
[texts]Glorifying God in the fires : a discourse delivered in the Second Presbyterian Church, Albany, November 28, 1861, the day of the annual thanksgiving, in the state of New York - Sprague, William B. (William Buell), 1795-1876
"Published by request of the young men of the congregation."
Keywords: Bible
Downloads: 2
[texts]The city intelligencer, or, Stranger's guide - V. & C
Edition for 1863 published under title: The stranger's guide and official directory for the city of Richmond. Cf. Crandall, 2677
Downloads: 79
[texts]An original wager : being a veracious account of a genuine bet - Vagabond
Bound in illustrated paper wrappers
Downloads: 143
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